I know lots of people like the Financial District/Embarcadero zone, but I tend to think that at least some hotels in that zone are in places that are too quiet at night. In general, I agree with Gallus50's assessment. Taking a look at some options for you, the Opal Hotel on Booking.com offers a cancellable booking for $86/night + tax, and includes breakfast. This is probably equivalent to your range of a $79 bid on Priceline, even without considering breakfast, because of extra Priceline fees. I would consider booking a backup like this, and then bidding carefully so you don't end up doing worse. Note this hotel would be in Priceline's Civic Center zone, but I think it's a nicer part (people with a more recent memory might like to comment).