The CBD zone abuts the corner of Bourbon & Canal, 1 block from where the party starts. The CC zone starts a two blocks away. But both stretch, so your hotel may be farther... In the CC zone, the nicer hotels (4* Sheraton, Hilton) tend to be right on Canal St, while the 2.5* hotels (Courtyard, Res. Inn) are up to a half mile away. First weekenders bidding CBD are mostly getting the Hyatt (for $60 - $80), which is also a bit of a hike. Be careful of going below 3* in the CBD, as there are some hotels that are very poorly reviewed there. In any case, don't hesitate to spend some of your hotel savings on a $5-$10 cab ride back to the hotel if you are tired, or it's late at night and the streets are deserted. And, please, try to see some of the nightlife besides Bourbon Street. Try Frenchmen St, just past the French Quarter, for a street party with lots of live music too.