Are you sure you really want to stay in Cathedral Hill? If you're going to be relying on Muni to get around, I'm not sure that it's the most convenient neighborhood for you. Cathedral Hill is only accessible by bus. You're close enough to the wharf if you take a bus for about 10 mins up Van Ness, but you're not really near anything else. I think you may be better off staying in an area like Union Square or the Embarcadero. Also consider the Civic Center area, which, although it isn't the prettiest neighborhood, it is very convenient for getting around on the muni, and less expensive than the other areas I've suggested.
