Key West hotels are up to $200 or more for this time of year. I go to Key West often but I've never used Priceline or Hotwire to book a room. I'm nervous about booking a room on Priceline or Hotwire for Key West, because of how spread out it is. I may try just one night and see what I get and then book the others elsewhere. Key West is tricky because if you want to be near Duval Street, where all the action is, you can't specify what area you want (not like NYC). Key West has hotels on the other side of the island where you would have to take a shuttle from the hotel and pay for that or drive and pay for parking to be in the town. If you want to be near Duval street, you might consider calling the Hilton or some B and B's and see what prices they offer. Key West is not cheap near Duval Street. I have stayed at the Hilton by Mallory Square and sometimes you can get a deal calling directly. I usually stay at the Banyan Tree Resort. They are one block away from Duval, and have kitchens (they are a Timeshare, but rent out on a daily basis), they are not cheap though, but I save money by eating breakfast and lunch in the room. Keep in mind February is high season in Florida, prices are at there highest. Let us know how you do.