Comfort Inn Airport and Conference Center 9600 Natural Bridge Rd Saint Louis, MO, 63134 (314) 427-7600 Amenities: Airport Shuttle, Fitness Center, Pool, Restaurant, Business Center According to its website, the airport shuttle is 24 hours. It's always a concern that 2* or 2.5* hotels only run shuttle between 6am-11pm, which is not good for late arrival or early departure. This property is a new listing. Used the HOTWIRE link on the board.