I strongly disagree... the hotel is right near Penn Station (so a lot of police nearby) and i have no idea why anyone would make (nor did i see) any negative comments regarding the area at night (it's no better/worse than any other area of Manhattan, imo). You will not find any hotel in NYC where 100% of the people are 100% happy (although this hotel is pretty darn close!), and you should instead focus on the overall message from the vast majority of the reviews.
It's also not far from Times Square... less than 10 blocks (which is nothing in NYC) and i will also add that you will likely spend far less time in Times Square than you think.
However, it's your money and your trip, so we'll move on, but if this was my stay it would be a very easy decision and this would be the one i would be choosing (only a very small minority of hotels will receive a 5.0/5.0 TA rating, and of those that do, they aren't offered at $165/nite).
For the HOTWIRE offers:
4.5* Times Square South $175
==> The Premier Hotel New York
4.5* Chelsea- 4.5* $176
==> Innside New York Nomad
5* Times Square North at $153/nite... full amenity set from BiddingHelper.com:
Restaurant, Fitness, Complimentary Breakfast, Free Internet, Hi-Speed Internet, Business
==> maybe the Westhouse but i'm not certain
4* Times Square North $163... i believe same hotel and full amenity set from BiddingHelper.com
Restaurant, Fitness, Free Internet, Hi-Speed Internet, Business, Blind Accessible, Deaf Accessible, Travel Accessible, Room Accessible, Bathroom Accessible, Handicapped Parking, Roll-in Shower, Pet Friendly
==> Crowne Plaza Hotel Manhattan
(if you wanted this one i would try to find a better way to confirm it's the same property)
Please remember to return to BetterBidding and use the PRICELINE and HOTWIRE links on the board to begin your travel purchases... or thru our sister site MAPSandHOTELS.com for your regular rate purchases.
Let us know what you decide to do for this trip or how we can be of further help.